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Leukotrine Modifiers

Leukotrine Modifiers are medications that interrupt the body's normal response to allergens, thus preventing asthma attacks in some patients. Asthmatics with primarily chemical triggers may have limited benefit from this family of drugs. Click on the medication name below to view more details.


Generic Name
Trade Name

montelukast sodium
Singular

zafirlukast
Accolate

zileuton
Zyflo

Singular®

(montelukast sodium)


Quiet Drug:

Oral leukotriene modifier


Singular (montelukast sodium) is a leukotriene modifier, a drug that interferes with the normal allergic response thus preventing bronchospasm, airway edema and inflammation.

Singular® is NOT to be administered by EMTBs per Maryland Medical Protocols


Drug Action:
Leukotriene modifier (antiasthmatic)


Dose:

5-10 mg daily in the evening


Supplied as:

Singular 4mg chewable tablets Singular 5 mg chewable tablets Singular 10 mg tablets


Accolate®

(zafirlukast)


Quiet Drug:

Oral leukotriene modifier


Accolate (zafirlukast) is a leukotriene modifier, a drug that interferes with the normal allergic response thus preventing bronchospasm, airway edema and inflammation. It inhibits bronchoconstriction in asthmatics caused by cold air and by sulfur dioxide as well as reducing the allergic response to some allergens.

Accolate® is NOT to be administered by EMTBs per Maryland Medical Protocols


Drug Action:
Leukotriene modifier (antiasthmatic)


Dose:

20 mg b.i.d.


Supplied as:

20 mg tablets

 


Zyflo™ filmtab®

(zileuton)


Quiet Drug:

Oral leukotriene modifier


Zyflo (zileuton) is a leukotriene modifier, a drug that interferes with the normal allergic response thus preventing bronchospasm, airway edema and inflammation. It inhibits bronchoconstriction in asthmatics caused by cold air as well as reducing the allergic response to some allergens.

Zyflo® is NOT to be administered by EMTBs per Maryland Medical Protocols


Drug Action:
Leukotriene modifier (antiasthmatic)

 


Dose:

600 mg q.i.d.


Supplied as:

600 mg tablets

 


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