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What
is Asthma?
ANATOMY
Air
enters the respiratory system through the nose (nasopharynx) and mouth
(oropharynx) and passes through the larynx (voice box) into the trachea.
At the carina, the trachea branches into the left and right main stem
bronchus. The bronchioles branch off of the bronchi and terminate in a
cluster of tiny air sacs called the alveoli. The alveoli are covered with
capillaries which receive the oxygen from the air in the alveoli and diffuse
the carbondioxide into the alveoli to be exhaled.
NORMAL
What
is asthma?
ASTHMATIC
Asthma
is reactive airway disease, a disease in which the smaller airways react
in response to a trigger such as an allergen or an irritant. It is airway
hypersensitivity with recerrent, reversible airway inflammation, broncho-constriction
(bronchospasm), and mucus gland secretion and hypertrophy (enlargement)
of the bronchial muscle. Asthma is a chronic-episodic order: The underlying
predisposition to asthma may be chronic, but attacks occur episodically
in response to some type of trigger.
Compare
the normal bronchus on the left with the asthmatic bronchus on the right.
Bronchospasm
is usually characterized by wheezes and prolonged expiration. The normal
respiratory cycle is about 1/3 inspiration and 2/3 expiration, or an inspiration/expiration
ratio of 1:2. In the asthmatic experiencing bronchospasm, the inspiration/expiration
increases to, for example, 1:4 due to the prolonged expiratory phase.
Cardiac
Asthma is a term sometimes used to describe congestive heart failure
(CHF). While CHF patients usually have a chief complaint of difficulty breathing
and have copious amounts of fluid in the lungs, they do not have the bronchospasm
associated with respiratory asthma. A key difference in the presentation
of CHF is that most patients maintain an inspiration/expiration ratio of
1:1 or 1:2 rather than experience the prolonged expiration phase of bronchospasm.
Click
here to listen to lung sounds, including wheezes
Common
Asthma Triggers
Allergens:
Cats/cat hair - Dogs/dog hair - feathers - foods - grass - hay - house dust
(mites) - medications - molds - pollen - roaches - trees - weeds
Chemicals:
Colognes/perfumes - cosmetics/hair sprays/lotions - detergents/soaps - vehicle
exhaust fumes - household & industrial cleaners - outside dust - paint
products/strippers/thinners
Weather:
Cold weather - rapid temperature changes - in and out of buildings temperature
changes
Emotional
Stress
Infections,
especially respiratory infections
Ingestants:
alcohol - spicy foods
Irritants:
Tobacco smoke - smoke from burning - harsh chemicals
Physical
Exercise (exercise induced asthma)
Asthma
Statistics
Centers
for Disease Control & Prevention reports that asthma:
affects
4.8 million children under 18 years old
accounts
for 1 in 6 pediatric Emergency Department visits
is
the #1 cause of hospitilization in children under 15 years old (200,000/year)
death rate
rose 78% in patients under 19 years old between 1980 & 1993
HOME
death
rate per 100,000 aged 5-34 years has nearly tripled since 1979
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