Leukotrine Modifiers are medications that interrupt the body's normal response to allergens, thus preventing asthma attacks in some patients. Asthmatics with primarily chemical triggers may have limited benefit from this family of drugs. Click on the medication name below to view more details.

Singular®

(montelukast sodium)

Quiet Drug:

Oral leukotriene modifier

Singular (montelukast sodium) is a leukotriene modifier, a drug that interferes with the normal allergic response thus preventing bronchospasm, airway edema and inflammation.

Singular® is NOT to be administered by EMTBs per Maryland Medical Protocols

5-10 mg daily in the evening

Singular 4mg chewable tablets Singular 5 mg chewable tablets Singular 10 mg tablets

Accolate®

(zafirlukast)

Quiet Drug:

Oral leukotriene modifier

Accolate (zafirlukast) is a leukotriene modifier, a drug that interferes with the normal allergic response thus preventing bronchospasm, airway edema and inflammation. It inhibits bronchoconstriction in asthmatics caused by cold air and by sulfur dioxide as well as reducing the allergic response to some allergens.

Accolate® is NOT to be administered by EMTBs per Maryland Medical Protocols

20 mg b.i.d.

20 mg tablets

Zyflo™ filmtab®

(zileuton)

Quiet Drug:

Oral leukotriene modifier

Zyflo (zileuton) is a leukotriene modifier, a drug that interferes with the normal allergic response thus preventing bronchospasm, airway edema and inflammation. It inhibits bronchoconstriction in asthmatics caused by cold air as well as reducing the allergic response to some allergens.

Zyflo® is NOT to be administered by EMTBs per Maryland Medical Protocols

600 mg q.i.d.

600 mg tablets